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In vitro reverse mutation bacterial tests according to the standard protocol have not been performed with sulfamethoxazole and trimethoprim in combination. An in vitro chromosomal aberration test in human lymphocytes with sulfamethoxazole/trimethoprim was negative. In in vitro and in vivo tests in animal species.sulfamethoxazole/trimethoprim did not damage chromosomes. In vivo micronucleus assays were positive following oral administration of sulfamethoxazole/trimethoprim. Observations of leukocytes obtained from patients treated with sulfamethoxazole and trimethoprim revealed no chromosomal abnormalities.

Get emergency medical help if you have any of these signs of an allergic reaction . hives. difficult breathing. swelling of your canadian pet pharmacy online. face.lips.tongue.or throat.

cold or flu symptoms.swollen gums.painful mouth sores.pain when swallowing.skin sores.

As with all drugs containing sulfonamides.caution is advisable in patients with porphyria or thyroid dysfunction.

Through the years I have had very bad sinus infections & out of many antibiotics Bactrim is the only one that helps me. Never had any side effects from Bactrim ??

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